Novel Pharmacological Therapies in Heart Failure

Recent advances in pharmacology have introduced new therapies that improve survival, reduce hospitalizations, and enhance quality of life in heart failure patients.

Key Highlights:

  • Sodium-glucose cotransporter 2 inhibitors: Improve cardiac outcomes beyond glycemic control.
  • Angiotensin receptor-neprilysin inhibitors: Reduce mortality and hospitalizations in reduced ejection fraction heart failure.
  • Selective myosin modulators: Enhance cardiac contractility without increasing oxygen demand.
  • Anti-inflammatory agents: Target systemic inflammation contributing to heart failure progression.
  • Tailored therapy: Personalized medication combinations based on patient profile optimize outcomes.

Emerging pharmacological treatments are reshaping heart failure management by addressing multiple pathophysiological pathways and improving patient prognosis.

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